Stubborn Creatures: Dormant Staphylococcus aureus

Dormant Cells of Staphylococcus aureus Are Resuscitated by Spent Culture Supernatant

We describe the first in vitro model of dormancy in Staphylococcus aureus, showing that cells are generated which can be resuscitated by addition of spent medium supernatant taken from cultures of the same organism. Over 30 days, culturable counts in dormant cultures of S. aureus SH1000 fell from 10(6)-10(7) cfu/ml to <10 cfu/ml as measured by the Most Probable Number method in liquid culture, ...

Staphylococcus aureus

Staphylococcus aureus

Staphylococcus aureus is a bacterium that is a member of the Firmicutes, and is frequently found in the human respiratory tract and on the skin. Although S. aureus is not always pathogenic, it is a common cause of skin infections (e.g. boils), respiratory disease (e.g. sinusitis), and food poisoning. Disease-associated strains often promote infections by producing potent protein toxins, and exp...

Staphylococcus Aureus

To date, 21 different staphylococcal enterotoxins have been described (known by letters of the alphabet, A V, although a few letters are missing from the sequence). All are heat stable, water-soluble proteins and retain their activity in the digestive tract after ingestion. Staphylococcal enterotoxin A (SEA), either alone, or in combination with other staphylococcal enterotoxins, is the one mos...

Reduced sensitivity of staphylococcus aureus to vancomycin

Introduction: Staphylococcus aureus is one of the most common causes of infections in hospitals and vancomycin is used for the treatment of methicillin resistant S, aureus infections. Therefore, imergence of Staphylococcus aureus with reduced sensitivity to vancomycin is a serious problem. The aim of this study was to investigate the prevalence of Staphylococcus aureus with reduced suscep...